Detalhe da pesquisa
1.
The Translational Landscape of the Human Heart.
Cell;
178(1): 242-260.e29, 2019 06 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31155234
2.
A high-resolution map of human RNA translation.
Mol Cell;
82(15): 2885-2899.e8, 2022 08 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35841888
3.
Inhibition of IL11 Signaling Reduces Aortic Pathology in Murine Marfan Syndrome.
Circ Res;
130(5): 728-740, 2022 03 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35135328
4.
IL-11 is a crucial determinant of cardiovascular fibrosis.
Nature;
552(7683): 110-115, 2017 12 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29160304
5.
A Neutralizing IL-11 Antibody Improves Renal Function and Increases Lifespan in a Mouse Model of Alport Syndrome.
J Am Soc Nephrol;
33(4): 718-730, 2022 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35140116
6.
IL11 Stimulates IL33 Expression and Proinflammatory Fibroblast Activation across Tissues.
Int J Mol Sci;
23(16)2022 Aug 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36012165
7.
IL11 Activates Pancreatic Stellate Cells and Causes Pancreatic Inflammation, Fibrosis and Atrophy in a Mouse Model of Pancreatitis.
Int J Mol Sci;
23(7)2022 Mar 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35408908
8.
IL11 is elevated in systemic sclerosis and IL11-dependent ERK signalling underlies TGFß-mediated activation of dermal fibroblasts.
Rheumatology (Oxford);
60(12): 5820-5826, 2021 12 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33590875
9.
Fibroblast-specific IL11 signaling drives chronic inflammation in murine fibrotic lung disease.
FASEB J;
34(9): 11802-11815, 2020 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32656894
10.
Antibody-mediated neutralization of IL11 signalling reduces ERK activation and cardiac fibrosis in a mouse model of severe pressure overload.
Clin Exp Pharmacol Physiol;
48(4): 605-613, 2021 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33462828
11.
Widespread Translational Control of Fibrosis in the Human Heart by RNA-Binding Proteins.
Circulation;
140(11): 937-951, 2019 09 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31284728
12.
Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Nonalcoholic Steatohepatitis.
Gastroenterology;
157(3): 777-792.e14, 2019 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31078624
13.
IL11 stimulates ERK/P90RSK to inhibit LKB1/AMPK and activate mTOR initiating a mesenchymal program in stromal, epithelial, and cancer cells.
iScience;
25(8): 104806, 2022 Aug 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35992082
14.
Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease.
Nat Commun;
13(1): 7497, 2022 12 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36470928
15.
Critical Conditions for Studying Interleukin-11 Signaling In Vitro and Avoiding Experimental Artefacts.
Curr Protoc;
1(9): e251, 2021 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34570432
16.
The pro-regenerative effects of hyperIL6 in drug-induced liver injury are unexpectedly due to competitive inhibition of IL11 signaling.
Elife;
102021 08 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34435951
17.
Similarities and differences between IL11 and IL11RA1 knockout mice for lung fibro-inflammation, fertility and craniosynostosis.
Sci Rep;
11(1): 14088, 2021 07 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34239012
18.
Molecular Dissection of Pro-Fibrotic IL11 Signaling in Cardiac and Pulmonary Fibroblasts.
Front Mol Biosci;
8: 740650, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34651016
19.
Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury.
Sci Transl Med;
13(597)2021 06 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34108253
20.
Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH.
Nat Commun;
12(1): 66, 2021 01 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33397952